Nasopharyngeal cryptococcosis   总被引：1，自引：0，他引：1  

R MALIK  P MARTIN  DI WIGNEY  DB CHURCH  W BRADLEY  CR BELLENGER  WA LAMB  VR BARRS  S FOSTER  S HEMSLEY  PJ CANFIELD  DN LOVE 《Australian veterinary journal》1997,75(7):483-488

Naturally occurring cryptococcosis in five cats, a dog and a koala is described. Involvement of the nasopharynx was documented in all patients, and nasopharyngeal mass lesions accounted for the major presenting complaints in four. Signs referable to nasopharyngeal disease included snoring, stertor, inspiratory dyspnoea and aerophagia. Diagnoses were made by caudal rhinoscopy using a retroverted flexible endoscope, vigorous orthograde flushing with saline, or at necropsy. Concurrent cryptococcal rhinitis was present in all cases, although involvement appeared limited to the caudal nasal cavity in most cases. Typical signs of nasal cavity disease, such as sneezing and nasal discharge, were often absent. Treatment of nasopharyngeal cryptococcosis should include physical dislodgement or debulking of lesion(s) to provide immediate alleviation of upper airway obstruction, followed by systemic antifungal therapy to eliminate residual infection from the nasal cavity. Infections caused by Cryptococcus neoformans var gattii accounted for a disproportionately large number of these cases.  相似文献   

Amoebic meningoencephalitis caused by Balamuthia mandrillaris in an orang utan     

PJ CANFIELD  L. VOGELNEST  ML CUNNINGHAM  GS VISVESVARA 《Australian veterinary journal》1997,75(2):97-100

Objective
To describe a case of meningoencephalitis caused by Balamuthia mandrillaris in an orang utan.
Design
A pathological case report.
Animal
A 20 years old male orang utan (Pongo pygmaeus).
Procedure
The disease process was investigated by clinical pathology, necropsy, histopathology and immunofluorescence labelling.
Results
The orang utan developed sudden onset of depression, lethargy, inappetence and apparent head pain. The condition was considered to be related to a 2 year history of upper and lower respiratory disease, and the animal was placed on antibiotics after extensive testing. By the seventh day the animal had become ataxic and disoriented and a brain abscess was suspected. He died on the ninth day of illness. At necropsy, and subsequent sectioning, the brain showed multiple circular, soft, white to grey brown areas of varying size, the largest being in the left temporal (3.5 cm diameter) and right occipital (2.5 cm diameter) regions of the cerebrum. Histological examination of these regions revealed many amoebic trophozoites and occasional cysts associated with areas of haemorrhage and inflammatory necrosis. The trophozoites were packed in perivascular spaces and their nuclei often contained two or more prominent nucleoli. Immunofluorescent labelling of histological sections suggested that the agent was B mandrillaris.
Clinical implications
This report provides further evidence that B mandrillaris , a free living amoeba, can act as a pathogen in animals as well as people, and cause fatal meningoencephalitis. Along with Naegleria and Acanthamoeba spp, B mandrillaris should be considered amongst the causes of acute onset meningoencephalitis in animals.  相似文献   

Serological characterisation of Haemophilus parasuis isolates from Australian pigs   总被引：2，自引：0，他引：2  

PJ BLACKALL  VJ RAPP-GABRIELSO†  DJ HAMPSON‡ 《Australian veterinary journal》1996,73(3):93-95

A total of 31 isolates of Haemophilus parasuis obtained from Australian pigs were serotyped by the Kielstein-Rapp-Gabrielson scheme. The isolates were assigned to serovar 1 (1 isolate), serovar 2 (1 isolate), serovar 4 (4 isolates), serovar 5 (7 isolates), serovar 9 (2 isolates), serovar 10/7 (4 isolates), serovar 12 (1 isolate) and serovar 13 (6 isolates). The remaining 5 isolates could not be assigned to a serovar. Two different serovars (5 and 13) were detected in one herd. The only 2 isolates obtained from clinically normal pigs (from the same herd) were serovar 9. The common serovars were isolated from pigs with pneumonia as well as from pigs with conditions of the Glässer's disease type. The serological heterogeneity amongst Australian isolates of H parasuis has important implications for the use of vaccines to control Glässer's disease.  相似文献   

Priorities for plants     

Waller D 《Science (New York, N.Y.)》1992,256(5059):1055-1056

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Feline attractant, cis,trans-nepetalactone: metabolism in the domestic cat     

G R Waller  G H Price  E D Mitchell 《Science (New York, N.Y.)》1969,164(885):1281-1282

cis,trans-Nepetalactone, the biologically active component of catnip, was force-fed to the domestic cat. When the (14)C-labeled compound was fed, 86 to 94 percent of the radioactivity was recovered in the urine, 1 to 2 percent was found in the feces, and 1 to 12 percent was collected as carbon dioxide. The major (50 to 75 percent) metabolite was alpha-nepetalinic acid, which was excreted in the urine together with small amounts of dihydronepetalactone, unchanged cis,-trans-nepetalactone, and several unidentified compounds. No marked physiological or histological eflects were observed when 20 to 80 milligrams of cis, trans-nepetalactone was administered orally. This is the first report on the metabolism of a mammalian attractant.  相似文献   

Stratigraphic data and length of the synodic month     

Hazel JE  Waller TR  Pannella G  Macclintock C 《Science (New York, N.Y.)》1969,164(3876):201-202

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Comment on "A green algal apicoplast ancestor"     

Waller RF  Keeling PJ  van Dooren GG  McFadden GI 《Science (New York, N.Y.)》2003,301(5629):49; author reply 49

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Chronic effects of reduced dissolved oxygen on Daphnia magna     

David H. Homer  William T. Waller 《Water, air, and soil pollution》1983,20(1):23-28

Daphnia magna, initially exposed when less than 48 h old, were maintained at reduced dissolved oxygen (DO) concentrations for 26 days. Exposure was accomplished in a continuous flow recirculating water system. Number of days to first brood, number of young in the first brood, total number of young produced, and dry weight were parameters measured. Statistical analyses show the Daphnia exposed to the lowest DO concentration tested (1.8 mg l^?1) had significantly reduced responses for all parameters measured. In addition, the organisms exposed to 2.7 mg l^?1 O₂ gained less weight than did the controls.  相似文献   

Evidence of molecular heterogeneity for generalised glycogenosis between and within breeds of cattle   总被引：1，自引：0，他引：1  

PJ HEALY  PJ NICHOLLS  F. MARTINIUK†  S. TZALL†  R. HIRSCHHORN†  JMcC HOWELL† 《Australian veterinary journal》1995,72(8):309-311

SUMMARY Northern analyses revealed normal levels of acidic α-glucosidase mRNA in cultured fibroblasts from a Shorthorn calf affected with glycogenosis but a gross deficiency in an affected Brahman calf. Analyses of acidic α-glucosidase activity, relative to that of other lysosomal enzymes, in blood mononuclear cells revealed greater variation within and between Brahman herds than Shorthorn herds. A Msp1 restriction fragment length polymorphism associated with glycogenosis in Brahmans was not found in Shorthorns. These results are considered in relation to molecular heterogeneity for AAG deficiency in cattle and its implications for disease control programs.  相似文献   

Disease of geese caused by a new herpesvirus   总被引：3，自引：0，他引：3  

PJ KETTERER  BJ RODWELL  HA WESTBURY†  PT HOOPER†  AR MACKENZIE‡  JG DINGLE§  HC PRIOR 《Australian veterinary journal》1990,67(12):446-448

A goose flock farmed outdoors in south-eastern Queensland suffered an outbreak of peracute disease with high death rate (97%). Small button ulcers and large plaques overlying lymphocyte aggregates were present on the mucosa of the small intestine of affected birds. Small white foci of necrosis and focal haemorrhages were seen in the livers. Numerous intranuclear inclusion bodies were observed microscopically in hepatocytes and a herpesvirus which grew rapidly in chicken kidney cells was isolated from tissues. Duck virus enteritis (DVE) was suspected but DVE antiserums failed to neutralise the virus. Further serological studies with a limited range of known avian herpesviruses have failed to identify the virus. Experimental transmission resulted in high mortality in geese (100%), lower mortality in ducklings and nil mortality in chickens. Surveillance studies showed no evidence of infection in domestic and wild birds beyond the original farm and the infection appears not to have been established in the area. Wild ducks, which were frequent visitors to the farm dam, were considered the most likely source of the infection.  相似文献